RSV is a highly transmissible seasonal virus which can be responsible, in some cases, for unpredictable but potentially severe outcomes in infants. It is one of the few remaining paediatric infectious diseases which, as yet, has no preventative option for all infants. RSV is the most frequent cause of respiratory disease, which can include bronchiolitis and/or pneumonia, in infants and is a leading cause of hospitalizations, most of which are in otherwise healthy infants born at term. This symposium includes a review of the epidemiology and substantial burden associated with RSV in infants while considering the impact of the COVID global pandemic, as well as the molecular basis of RSV infection. An interactive panel of experts discusses these topics that impact RSV.

• Maria Tsolia – Opening Remarks
• Fernanda Rodrigues – A Closer Look at the Evolving Epidemiology of RSV Due to COVID
• Chiara Azzari – The Extended Reach of the Substantial RSV Burden of Disease
• Ultan Power – Understanding Neutralizing Antibody Protection through RSV Virology and Pathogenesis
• Live Q&A
• Maria Tsolia – Summary and Closing Remarks

This session focuses on raising awareness of the impact of childhood invasive meningococcal disease (IMD) and advances in preventative strategies. The distinguished faculty provides expert perspectives on key challenges as well as discuss the most important unmet needs which still need to be addressed to reduce the burden of disease in infants, children and adolescents, and the impact on their families. This satellite symposium specifically intended for healthcare professionals (HCPs) is sponsored by Sanofi on the occasion of the 40th Annual Meeting of the European Society for Paediatric Infectious Diseases, 9-13 May 2021. Individual medicinal products that may be referred to during this session may not be authorised/licensed or available in all countries. Content, where applicable, is based on the European Summary of Product Characteristics (SmPC). Please consult prescribing information in your country of practice, current to the date of viewing this session, as information may vary from country-to-country.

Prof. Ener Cagri Dinleyici
Professor of Paediatrics at the Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, Turkey.

• Georgina Tzanakaki – Welcome and introduction
• Elena Moya, Ener Cagri Dinleyici & Georgina Tzanakaki – Round table discussion and expert perspectives on challenges in childhood IMD epidemiology, impact of the COVID-19 pandemic, vaccination trends and unmet needs
• Georgina Tzanakaki – Current progress and gaps in childhood vaccination to prevent IMD
• Elena Moya – The continuing childhood burden of IMD: the patient and family perspectives
• Ener Cagri Dinleyici – The MenACYW vaccine armamentarium against IMD in paediatric populations
• Live Q&A

The establishment of a global adolescent immunization platform – a schedule of health visits for administration of recommended adolescent vaccines – can provide broad health benefits for this population. As well enhancing protection against vaccine-preventable diseases, immunization platforms act as a hook to bring adolescents into the doctor’s office for other physical, psychosocial, and preventive services, providing opportunities for HCPs to assess and support overall adolescent health and wellbeing. In this symposium, the expert panel discusses the role of immunization platforms and the important principles of adolescent health supervision and anticipatory guidance, including screening for psychosocial concerns.

• Jonathan Klein – Introduction to global adolescent immunization platforms
• Catherine Weil-Olivier – The current portrait of adolescent immunization
• Nuray Kanbur – Factors impacting the landscape of adolescent health
• Asha Pemberton – Developing an approach for adolescent care: Health supervision and anticipatory guidance
• Pierre-André Michaud – Setting the scene for global assessments of adolescents’ situations and needs
• All Faculty – Panel discussion: Immunization as a framework for improving adolescent health

The Neisseria symposium will provide an overview of MenB vaccination in infants and adolescents as well as novel, emerging vaccine strategies. Prof. Muhamed-Kheir Taha will cover real-world evidence for 4CMenB in infants and important factors in driving recommendations. Prof. Lee Harrison will discuss the evidence and rationale for adolescent vaccination programmes. Lastly, Dr. Rino Rappuoli will highlight new scientific innovations in the field of Neisseria disease prevention.

Vana Papaevangelou
Clinical paediatrician in tertiary teaching hospitals since 1996.
She is a member of the National committee for COVID-19 response, the National Advisory Board for Immunization Practices, the scientific committee of the Greek CDC, the National Hepatitis Board and the Viral Hepatitis Prevention Board. She is a Board member of ESPID since May 2019.

Muhamed-Kheir Taha
Head of the Invasive Bacterial Infections Unit at the Institut Pasteur in Paris, France. He is also Head of the French National Reference Centre for Meningococci and Haemophilus influenzae and Head of the WHO Collaborating Centre for Meningitis.
Professor Taha is the current President of the European Meningococcal and Haemophilus Disease Society (EMGM).

Lee Harrison
Infectious Diseases Physician, Professor of Medicine and Epidemiology, and Director of the Center for Genomic Epidemiology at the University of Pittsburgh. He is also an Adjunct Professor in the Department of International Health at Johns Hopkins Bloomberg School of Public Health.

Rino Rappuoli
Global Head of Vaccines R&D at GSK and is based in Siena, Italy. He is also Honorary Professor of Vaccinology at Imperial College, London, and Extraordinary Professor of Molecular Biology at the University of Siena.
As the founder of the GSK Vaccines Institute for Global Health (GVGH), Dr Rappuoli is among the world’s foremost scientific leaders dedicated to the sustainability of global health.

• Vana Papaevangelou – Welcome and Introduction
• Muhamed-Kheir Taha – State of the art: MenB prevention today
• Lee Harrison – Coming of age: MenB adolescent vaccination
• Rino Rappuoli – Looking to the future
• Vana Papaevangelou – Panel discussion with questions from the audience
• Rino Rappuoli – Concluding remarks